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How Adenomyosis Affects the Uterus Adenomyosis is a gynaecological condition in which the tissue that normally lines the inside of the uterus grows into the muscular wall of the uterus. As this tissue continues to behave like normal endometrial tissue during each menstrual cycle, it can cause the uterine walls to become thicker and enlarged. This often results in pain, heavy menstrual bleeding,...